Research Proposal on Cardiovascular Research Example | Topics and Well Written Essays - 250 words

On Cardiovascular - Research Proposal Example In many cases, however, it is not possible to arrive at a specific etiologic diagnosis, and thus it is often more desirable to classify the cardiomyopathies into one of three types dilated, restrictive, hypertrophic on the basis of differences in their pathophysiology and clinical presentation (Braunwald, 2005, 13-78). Current literature concerning the molecular mechanism of this disease and attendant cardiac failure will be searched to find out the gap in the current knowledge. Sebastini et al. in their 2009 article, discusses the molecular events linking mtDNA defects to cardiac hypertrophy as the cause of congestive heart failure. It has been suggested that the cellular and molecular mechanism of cardiac dysfunction is related to energy derangements and increase of mitochondrial derived reactive oxygen species. There is a continuous cardiomyopathic remodelling in the pathogenesis of congestive heart failure has been attributed to mitochondrial proliferation and the factor of mechanical dysfunction (Sebastini et al., 2009). Moorjani et al. (2006) investigated the phenomenon of activation of apoptotic Caspase cascade during the transition to pressure overload induced heart failure.

Environmental Scan Assignment Example | Topics and Well Written Essays - 1000 words

Environmental Scan - Assignment Example The program is solely responsible for health services and training opportunities, along with valuable educational programs. Regina Food Bank has been sustaining its operations from past many years. However external forces tend to affect operations of this charitable organization. There are four major forces in external environment as per PEST model such as political, economic, social and technological forces. This project has been incorporated in Regina located in Canada. Political power is in favor of Regina Food Bank. Its main aim is to eradicate any form of hunger issues from the country. The government had recently announced a lump sum amount to be donated to Regina Food Bank. This kind of investment would be done in terms of capacity building in community and voluntary sector. Political conditions at times are not stable due to frequent elections and this in turn proves to be a threat for charitable organizations. Economic factors mainly comprise of effect of recession on charitable organization. This encompasses various phenomenons like lower income of donor, increased service demand and stiff competition in context of declining funds of government. Job security is a vital issue for donors and this affects operations of charitable organizations. When disposable income is low then it negatively affects donation habits of individuals. Reduction in interest rates is good for businesses and home-owners but it has adversely affected charities. Market volatility reduced overall income from investments and reserves for many firms. The charities usually are dependent on investment factor. This kind of dependency will be influential since larger portfolio portion is held in shares. Market volatility also plays a major role for charities in context of pension funds. Pension funds are usually bounded within equities and hence declination in stock value creates large deficits. Financial instability and low interest

Proposed HR Program for CompuLearn Essay Example for Free

Proposed HR Program for CompuLearn Essay CompuLearn is a private sector provider of IT-based teaching and learning programmes in business and management based in the UK, with corporate headquarters in Preston, Lancashire and with trading centers in Mumbai, Nairobia and Dubai. Its current global market is focused in the Middle East, Asia, Africa, with 200 education centers in 30 countries. CompuLearn partners with UK universities which validates its programs so that   students are able to qualify in the University programs leading to academic degrees. Its current manpower complement numbers 50 employees mostly based in the corporate office in Preston, Lancashire doing the following functions: Program Development, Customer Service, HR, Marketing, Finance, Sales, IT, Quality Assurance. CompuLearn has embarked on a mission to be market leader in e-learning delivery of University validated programs and foremost learning company in the world. It is on an expanded growth program and it adopted a new strategy to extend to 500 education centers in 60 countries over a span of 3 years. The role of HR is very critical in this new strategy, which is to attract top IT experts. It could be a relatively easy task if not for the following: 1. There is a high turn over in the IT industry in UK and new employees leave after only one month for a new job that offers better pay. 2. CompuLearn has a limited training system in place. Its strategy is to recruit highly trained staff instead of training them in house. The allocated budget for training is almost used up and was used to train the Sales team. 3. Employees have limited management skills as they are mostly technical staff whose training is not in the soft skills development. 4. The company does not have a Performance Appraisal System in place. 5. The staff at the corporate headquarters do not have a comfortable relationship with the staff of the UK universities largely due to complaints of attitude. 6. The HR Director’s strength is in micro-managing and does not have expertise in long-term management plans for the company employees. The Limitations and Constraints Faced by the Company The HR Department will play a very strategic role in supporting the growth of CompuLearn. Among other things, it needs to address the following limitations and constraints faced by the company, whether internally caused or faced by the industry in general: 1. The high turn over rate in the IT industry in UK 2. The lack of a professional or well-developed training and development program for employees 3. The employees’ limited skills in management, customer service and other soft skills 4. The lack of a well-placed Performance Appraisal System 5. The not-so-friendly attitude of the academic staff of the Universities towards the company employees at the corporate headquarters 6. The limited knowledge and skills of the HR Director in long-term planning for the management of the employees Recommendations The HR strategies recommended are based on the following assumptions: 1. Budget The company is working on a limited budget, which is just around 30% of the  annual budget of 25,000 Euros. 2. Lead Department The HR Department will take the lead in implementing the strategies. The HR Director shall formally appoint the section heads to serve as lead persons in implementing the strategies in their respective sections. The HR Director has the free hand in creating working committees to participate in the entire process from planning to implementation. The process will be participatory and with some amount of consultation from the employees. 3. Timetable The strategies are proposed for implementation on a focused basis within the first year (Year 1 Month 1 to Month 12). Beginning Year 2 (Month 13) the focus of the activities will be on monitoring, evaluation, and implementation of improvements. 4. HR Management Perspective/Model Available literature identify different HR Management models that attempt to explain the various strategies adopted by different companies. General classifications fall under the â€Å"soft† and â€Å"hard† models, based on the definitions of employees considered as either â€Å"human† or â€Å"resource†. The hard versions consider employees as resource and adopt a rational approach to managing them, aligning their HR strategies with the strategies of the business. The soft version, on the other hand, considers employees as human and adopts strategies to train and develop them (Bratton and Gold, p. 5). The recommendations adopted in this case will be based more on the soft version of human resource management. Focus will be more on training and development as well as in developing commitment from employees. A limited form of the hard version will however allow the HR to link the strategies with the overall corporate strategy of the company. In analyzing the challenge faced by CompuLearn, a simplistic framework was designed around the following questions, based on the limitations/constraints faced by the company and to become the basis for the strategies: 1. On the high turn-over rate in the IT industry How can CompuLearn keep its employees from leaving the company after short- term engagement only? Or how can the company motivate its employees to stay longer? 2. On the lack of a professional training and development program Should the company train in-house or continue to hire experts from outside? 3. On the employees’ limited skills in management, customer service, and other soft skills. How can the employees learn the soft skills and apply them at work? 4. On the lack of a well-placed Performance Appraisal System Is there a need to formulate or adopt a Performance Appraisal System? 5. On the not-so-friendly attitude of the academic staff of the Universities towards the company employees at the corporate headquarters How can there be a more cordial relationship between the two parties? How can the company make the employees appreciate the importance of having good relations with the University staff? Can this be done through training or should the company replace those who transact with the University staff with other company employees, either through job rotation or job enrichment? 7. On the limited knowledge and skills of the HR Director in long-term planning for the management of the employees. Should the HR Director undertake refresher courses in management? Or should the company hire a new HR person who has the skills in long term planning to assist the HR Director? Below is a presentation of the proposed HR strategies and programs, in matrix form,   that can be implemented under the leadership of the HR Director. They are composed of both short term and long term strategies. The short-term strategies are those that can be immediately implemented, within the first six months from the time the recommendations will be adopted. The long term strategies are those that can be adopted over a longer period and on a continuing basis like the periodic reviews of policies and developing a system whereby improvements can take place every so often whenever warranted. It will be observed that most of the strategies will be newly introduced to the company and it can be expected that certain difficulties will be met. This will include among other things, resistance to the changes to be introduced, the difficulty of the HR Department to implement them for lack of the appropriate knowledge and skills, and with some â€Å"difficult† employees. This is all part of the process of the HR accepting the initial resistance  to the changes. The HR should be firm and consistent but at the same time adopting an attitude of openness and willingness to see through the improvements. Education and training are two important components of an empowered workforce. The saying that a company is only as good as its weakest employee is very much applicable here. Each employee is responsible for knowing about his company and performing according to the expectations set at the time of his engagement. However, it is the job of HR to find the employees who have the potential to learn more and continuously give them the opportunities to develop their knowledge and skills.

Byzantium: faith and power 1261 - 1557 :: essays research papers

Byzantium – the state which has brought in the big contribution to development of culture to Europe of middle ages. Here the Christianity for the first time became an official religion. Christianity affected the Byzantine art. In Byzantine art the main subject of paintings – icons (Greek – image) were holy figures: Christ, the Virgin Mary, the saints, and the apostles. One of the most famous is icon with Archangel Gabriel, Byzantine (Constantinople or Sinai?), 13th century. There is the exhibition devoted to the art of Byzantine civilization at the Metropolitan Museum of Art. The exhibition begins in 1261, when the capital Constantinople was restored to imperial rule, and concludes in 1557. It is last period of existence of Byzantium and time of last blossoming of its culture. One of the great example of Byzantine icons is Two-Sided Icon with the Virgin Pafsolype and Feast Scenes and the Crucifixion and Prophets, Byzantine (Constantinople) second half of the 14th century. On the observe side there is the picture of the Virgin and Child surrounded by ten feast scenes. At the upper left corner we can see Archangel Gabriel tells to the Virgin that she will have a Child. The last scene is the death of the Virgin. On the reserve side we can see the Crucifixion of the Christ. Mother and apostle stand near Christ with a great sorrow on their faces. The other great icon from that epoch is icon with Saint Catherine of Alexandria and Scenes of her Passion and Martyrdom, Sinai, 13th century. The image of Saint Catherine also surrounded by twelve small scenes from her life. There are scenes of her imprisonment and torture, and we can see that angel never leaves her. The last scene is her beheading. If we look at this icon we can see that the Saint Catherine holds the cross on her hands; it means that she was murdered because of her faith in Christianity. She dressed as a royal person. The background of an icon symbolizes divine essence. For example, gold – Divine light, white – cleanliness of the Christ and light of his Divine, green -

Jane Eyre :: Literature Religion Papers

Jane Eyre    St. John Rivers makes some very intriguing choices in Jane Eyre. He is constantly faced with difficult decisions to make. Whether it be refusing his true love or moving to India to give his life serving others, there is always an interesting twist where St. John is concerned. His importance in the novel may be evident to readers, but they may not always understand his decisions and his actions. The choices he makes are exemplary of a man who has given his life to serve God and His people. St. John, at his introduction in the novel, is a clergyman with plans to become a missionary someday soon. This is not surprising for clergymen, according to Andrew F. Walls, author of The Missionary Movement in Christian History, since "a missionary was essentially a preacher, and a preacher should normally be a minister" (161). At this time, it was considered normal for a clergyman to become a missionary. But a missionary did have to be more than a clergyman. He also must have "common sense" and "competence," Walls says. St. John has all of these qualities and more, making him perfect for a life of sacrifice. St. John Rivers is introduced into the novel as a savior. He takes Jane into his home and under his care when she believes to have reached the end of her road. It is here, at Moor House with St. John, that she is given a new beginning with a new identity, job, and, eventually, a family with St. John and his sisters. As a clergyman, St. John is a good, moral person whose intentions are to provide for his people and his family. He also eventually wants to become a missionary someday soon. Jane likes the idea of this and it is evident to readers that Jane admires St. John and loves him like the brother he has become to her. He even gives her a job as a teacher at a school for less fortunate children. It is here that she is introduced to Rosamond Oliver and her father. After meeting Rosamond Oliver through her teaching position and hearing her talk about St. John with admiration, Jane concludes that they are meant to be for each other. She goes to St. John with her allegations and he admits his love for her to Jane: [. . .] I

Contemporary Hawaiian Music Essay

There is a famous Hawaiian saying, â€Å"You know if the Hawaiian harmonies are good if they give you chicken skin† (Alternative Hawaii, 2002) and, I must say, listening to the online radio streaming of KCCN FM100 gave me goosebumps. Being more attuned to â€Å"Western pop† culture, it was a pleasantly refreshing experience for me to sit for an hour and listen to contemporary reggae, urban music and ragga with an island beat that’s truly Hawaiian. Fourteen original Hawaiian songs, including the Top 5 hits in KCCN charts, were played during a late afternoon program that also aired a couple of brief â€Å"Hele On† traffic news, a commercial each from Earth Share and Hawaii. gov, and 8 radio ads encouraging the people to participate at the ongoing 2010 Census. The DJ on deck did not talk much except to give quick, in-between plugs for a party event and to introduce songs. A distinctly noticeable feature in the contemporary Hawaiian music is its fondness to love and desire. The soulful songs I listened to speak of the excitement of love, romancing the heart of another or accepting a love’s rejection. But even though the lyrics contain sad words, the melody is always upbeat and sensual. The island reggae beat and the smooth ballad is very easy on the ears especially when instruments, like the ukulele, saxophone and native drums blend together to produce the perfect harmony. The result is one relaxed listener mentally transported in an island paradise in Hawaii, and its effect to music lovers is no less than rejuvinating the soul. I think KCCN FM100, being a radio station that plays modern hip-hop and soul Hawaiian music, carries the familiar radio spunk of other American hiphop stations. The DJ was very energetic and in a party mood, and even the traffic reporter was such a chipper in delivering traffic updates as a local RnB song played in the background. The advertisements aired between the 4:30-to-5:30pm radio show were mostly the varying versions of promoting the 2010 Census Count – explaining what the census results would mean to businesses, the improvement of social services and what it means to the future generation. I think delivering the message using both in English and the local dialect reveals a lot about the listeners’ profile of KCCN, which is a mixture of both modern and traditional Hawaiian folks. I also believe that although all local songs aired were sang in English, they always make it a point to bring out the traditional Hawaiian flavor. This much is obvious in both the songs and commercials played. Listening to KCCN and the music aired there makes me realize how global Hawaiian music can be in terms of its appeal to both young and old, locals and foreigners. Everybody can appreciate an island style music inspired by the world-loved Bob Marley and urban rhythm of the modern RnB.

How does the opening sequence of Gladiator and Saving Private Ryan raise the audiences expectations Essays

How does the opening sequence of Gladiator and Saving Private Ryan raise the audiences expectations Essays How does the opening sequence of Gladiator and Saving Private Ryan raise the audiences expectations Paper How does the opening sequence of Gladiator and Saving Private Ryan raise the audiences expectations Paper Essay Topic: Film Before the films Saving Private Ryan and Gladiator have begun the audience already has an expectation of the film based on the actors and directors of the two movies. Both films have Auteurs as directors and have famous actors playing the protagonist of the movies. This will give the audience expectations of the film based on the status of the actors and directors. Both directors Steven Spielberg and Ridley Scott have directed impressive films in all types of genre. Tom Hanks and Russell Crowe play the protagonists in the two films (Tom Hanks-Saving Private Ryan Russell Crowe-Gladiator) which are shown in the posters advertising the two films; these also show the genre of the two movies. The opening sequence of the two movies features montages with very little background sound. Gladiators opening shots show a close up of a hand being run through a field. The hand has a ring on showing that the man is married. The field is bathed in golden light; strong contrast to the first shot of the protagonist, which is lit with chiaroscuro. The successions of these two shots give us the impression that the hand belonged to the protagonist, Russell Crowe. Russell Crowe plays the general Maximus Deridius. The opening shots of Saving Private Ryan feature an Old man walking down a path in bright light on a sunny day. While the man is walking a group of people follow him down the path, telling the audience that this man is quite important. The man is walking in a graveyard and after walking to a particular grave he collapses crying. His sadness gives the impression that someone he knew and loved had died and was buried in that graveyard. The shot then switches to a group of men in a boat which again uses chiaroscuro. There is then a series of montages featuring close ups of the men in the boat. The emotions of the men are shown in the expressions on their faces and the dark shadowy light the scene is bathed in. The protagonist of the film Tom Hanks is then shown in a close up shot but it is different to the way that we are first shown Russell Crowe in Gladiator. The first time that we see Russell Crowe in Gladiator he looks deep in thought and with very little fear on his face. His clothes depict what class of man he is (wealthy, powerful,) and also show the genre of the film to be war as he is holding a sword and wearing armor. The first time that Tom Hanks is introduced his clothes show the genre of the movie in the same way as gladiator, but he is not instantly recognizable as the protagonist of the film; he looks just as scared as the other people on the boat and has no instant sign of authority. As the men approach the shore, the sound of gunfire can be heard, which tells the audience that a battle is happening and that these mens fear is the onslaught of battle. The opening sequence of both texts show the genre of the movie by using strong battle scenes and sounds and both introduce why Tom Hanks and Russell Crowe are the protagonists of the films. Russell Crowe walks through the ranks of his army and is referred to as General by many. The director uses this to show the authority of the character. The director of S. P. R shows Tom Hanks to be powerful by having take control of the disbanded army around him and he seems to be the least distressed by the battle going on around him. Both texts feature strong battle sequences in their opening scenes. The scenes are seen in a different way by the audience because inter-textuality will tell people that the Roman Army in Gladiator was unbeatable and the most powerful fighting force the world had ever seen. We know that the protagonist is a Roman general and we know that the opposing army is not strong enough to beat them from what has been said by the characters already so the audience has a basic idea of what to expect from the battle: the Romans are going to win. In S. P. R Tom Hanks and his army are put in an impossible position from the off set. When they hit the shore the sound of gunfire fills the air and immediately pushes them back towards the sea and in a seemingly impossible position. Tom Hanks role as the protagonist is emphasized by the way that the people around him all turn to him for orders when they first hit the shore and begin fighting. The fighting scenes in both films are shot with a hand held camera allowing the audience to feel as if they are in the battle themselves. In S. P. R a hand held camera is used from behind the German stationery guns on the bank to show how easily the Americans are being picked off from the beach. Close up shots in Gladiator show the expressions of the Roman army and none of them look scared or worried about the battle. During the battle they use close ups of the fighting to show the Roman army defeating the German army with ease. A close up of Russell Crowe is used when he turns around and almost kills one of his own men, only to stop and smile at him. This shows he is used to fighting dangerous battles and how undeterred by the fighting and the sounds around him he appears to be. The music in the two opening sequences is similar and is used to create the same affect on the audience. The slow first scenes of the two movies have very little sound as the directors want you to focus on the messages on the screen. The flag at the start of S. P. R symbolizes what the Americans were fighting for: the love of their country. Gladiator features a hand being run through a field which tells you little apart from that the hand belongs to someone who is married. The battle scenes in the two films have very little music but you can hear the sounds of the battle distinctly. In S. P. R the sounds of gunfire is very loud and the cries of the men screaming and yelling are quite disturbing. In Gladiator the sounds of clashing swords fills the air with cries coming only from the German army. Music is absent as it is normally used to project the emotions of the characters on screen onto the audience. In a scene with a strong battle there are so many emotions of so many people fighting that there wouldnt be enough music to symbolize what they were all feeling. I think that Gladiator raises the audiences expectations more in the opening sequences as they show the Roman army to be brutal and unmerciful which is shown more and more in the rest of the film. Saving Private Ryan has a brilliantly directed opening and gives the audience a real insight into what war is like. Yet the rest of the film goes downhill and doesnt give you what you would expect from the dazzling opening sequences.